The mechanism of (+) taxifolin’s protective antioxidant effect for •OH-treated bone marrow-derived mesenchymal stem cells

The mechanism of (+) taxifolin’s protective antioxidant effect for •OH-treated bone marrow-derived mesenchymal stem cells

Abstract The natural dihydroflavonol (+) taxifolin was investigated for its protective effect on Fenton reagent-treated bone marrow-derived mesenchymal stem cells (bmMSCs). Various antioxidant assays were used to determine the possible mechanism. These included •OH-scavenging, 2-phenyl-4, 4, 5, 5-te...

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Bibliographic Details
Main Authors: Xican Li, Hong Xie, Qian Jiang, Gang Wei, Lishan Lin, Changying Li, Xingmei Ou, Lichan Yang, Yulu Xie, Zhen Fu, Yamei Liu, Dongfeng Chen
Format: Article
Language:English
Published: BMC 2017-12-01
Series:Cellular & Molecular Biology Letters
Subjects:
(+) Taxifolin; bmMSCs
•OH damage
Antioxidant mechanism
Electron transfer
Fe2+ binding
Online Access:http://link.springer.com/article/10.1186/s11658-017-0066-9

Internet

http://link.springer.com/article/10.1186/s11658-017-0066-9

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