Nickel-catalysed retro-hydroamidocarbonylation of aliphatic amides to olefins

Converting the normally highly stable amide bond into different functionalities is a challenging task. Here the authors report a nickel-catalysed retro-hydroamidocarbonylation procedure, allowing the conversion of aliphatic amides into alkenes across a range of substrates.

Bibliographic Details
Main Authors: Jiefeng Hu, Minyan Wang, Xinghui Pu, Zhuangzhi Shi
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/ncomms14993