Regulatory T Cells in HIV Infection: Can Immunotherapy Regulate the Regulator?

Regulatory T cells (Tregs) have a dominant role in self-tolerance and control of autoimmune diseases. These cells also play a pivotal role in chronic viral infections and cancer by limiting immune activation and specific immune response. The role of Tregs in HIV pathogenesis remains poorly understoo...

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Bibliographic Details
Main Authors: Mohammad-Ali Jenabian, Petronela Ancuta, Norbert Gilmore, Jean-Pierre Routy
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Clinical and Developmental Immunology
Online Access:http://dx.doi.org/10.1155/2012/908314