Modulation of macrophage activation by prostaglandins

The effect of prostaglandtn E2, iloprost and cAMP on both nitric oxide and tumour necrosis factor-α release in J774 macrophages has been studied. Both prostaglandin E2 and iloprost inhibited, in a concentration-dependent fashion, the lipopolysaccharide-induced generation of nitric oxide and tumour n...

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Bibliographic Details
Main Authors: L. Sautebin, R. Carnuccio, F. D'Acquisto, M. Di Rosa
Format: Article
Language:English
Published: Hindawi Limited 1996-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/S0962935196000026