The opioid epidemic: a central role for the blood brain barrier in opioid analgesia and abuse

Abstract Opioids are currently the primary treatment method used to manage both acute and chronic pain. In the past two to three decades, there has been a surge in the use, abuse and misuse of opioids. The mechanism by which opioids relieve pain and induce euphoria is dependent on the drug crossing...

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Bibliographic Details
Main Authors: Charles P. Schaefer, Margaret E. Tome, Thomas P. Davis
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Fluids and Barriers of the CNS
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12987-017-0080-3