YBX-1 mediated sorting of miR-133 into hypoxia/reoxygenation-induced EPC-derived exosomes to increase fibroblast angiogenesis and MEndoT

YBX-1 mediated sorting of miR-133 into hypoxia/reoxygenation-induced EPC-derived exosomes to increase fibroblast angiogenesis and MEndoT

Abstract Background Myocardial fibrosis is a common pathophysiological change in cardiovascular disease, which can cause cardiac dysfunction and even sudden death. Excessively activated fibroblasts proliferate and secret excessive extracellular matrix (ECM) components, resulting in normal cardiac st...

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Bibliographic Details
Main Authors: Fengxia Lin, Zhicong Zeng, Yinzhi Song, Liang Li, Zijun Wu, Xiaoduo Zhang, Zhiwen Li, Xiao Ke, Xun Hu
Format: Article
Language:English
Published: BMC 2019-08-01
Series:Stem Cell Research & Therapy
Subjects:
Endothelial progenitor cell
Myocardial fibrosis
miR-133
Exosome
Y box binding protein 1
Online Access:http://link.springer.com/article/10.1186/s13287-019-1377-8

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http://link.springer.com/article/10.1186/s13287-019-1377-8

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