Angiotensin II type 1/adenosine A 2A receptor oligomers: a novel target for tardive dyskinesia

Angiotensin II type 1/adenosine A 2A receptor oligomers: a novel target for tardive dyskinesia

Abstract Tardive dyskinesia (TD) is a serious motor side effect that may appear after long-term treatment with neuroleptics and mostly mediated by dopamine D2 receptors (D2Rs). Striatal D2R functioning may be finely regulated by either adenosine A2A receptor (A2AR) or angiotensin receptor type 1 (AT...

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Bibliographic Details
Main Authors: Paulo A. de Oliveira, James A. R. Dalton, Marc López-Cano, Adrià Ricarte, Xavier Morató, Filipe C. Matheus, Andréia S. Cunha, Christa E. Müller, Reinaldo N. Takahashi, Víctor Fernández-Dueñas, Jesús Giraldo, Rui D. Prediger, Francisco Ciruela
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02037-z

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https://doi.org/10.1038/s41598-017-02037-z

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