Licochalcone D Induces ROS-Dependent Apoptosis in Gefitinib-Sensitive or Resistant Lung Cancer Cells by Targeting EGFR and MET

Licochalcone D Induces ROS-Dependent Apoptosis in Gefitinib-Sensitive or Resistant Lung Cancer Cells by Targeting EGFR and MET

Licochalcone D (LCD), a flavonoid isolated from a Chinese medicinal plant <i>Glycyrrhiza inflata</i>, has a variety of pharmacological activities. However, the anti-cancer effects of LCD on non-small cell lung cancer (NSCLC) have not been investigated yet. The amplification of <i>M...

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Bibliographic Details
Main Authors: Ha-Na Oh, Mee-Hyun Lee, Eunae Kim, Ah-Won Kwak, Goo Yoon, Seung-Sik Cho, Kangdong Liu, Jung-Il Chae, Jung-Hyun Shim
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Biomolecules
Subjects:
licochalcone d
non-small cell lung cancer
reactive oxygen species
apoptosis
Online Access:https://www.mdpi.com/2218-273X/10/2/297

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https://www.mdpi.com/2218-273X/10/2/297

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