Exon 11 homozygous mutations and intron 10/exon 11 junction deletions in the KIT gene are associated with poor prognosis of patients with gastrointestinal stromal tumors

Abstract Background Gastrointestinal stromal tumors (GISTs) with different types of mutations exhibit different clinical characteristics and prognosis. This study aimed to evaluate the prognostic value of mutations in KIT and PDGFRA in a large‐scale cohort of GIST patients with current therapy inclu...

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Bibliographic Details
Main Authors: Yan‐Ying Shen, Xin‐Li Ma, Ming Wang, Chun Zhuang, Bo Ni, Lin Tu, Qiang Liu, Wen‐Yi Zhao, Hui Cao
Format: Article
Language:English
Published: Wiley 2020-09-01
Series:Cancer Medicine
Subjects:
KIT
Online Access:https://doi.org/10.1002/cam4.3212