Stress Granule Dysregulation in Amyotrophic Lateral Sclerosis

Stress Granule Dysregulation in Amyotrophic Lateral Sclerosis

Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease with no current cure. ALS causes degeneration of both upper and lower motor neurons leading to atrophy of the innervating muscles and progressive paralysis. The exact mechanism of the pathology of ALS is unknown. However,...

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Bibliographic Details
Main Authors: Jessica Dudman, Xin Qi
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Cellular Neuroscience
Subjects:
amyotrophic lateral sclerosis
stress granules
protein aggregation
neurodegeneration
therapeutics
Online Access:https://www.frontiersin.org/articles/10.3389/fncel.2020.598517/full

Internet

https://www.frontiersin.org/articles/10.3389/fncel.2020.598517/full

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