Trisomy 11 as an Additional Chromosome Alteration in a Child with Acute Promyelocytic Leukemia with Poor Prognosis

The prognostic significance of the additional abnormalities to the t(15; 17) remains controversial. We report a case of promyelocytic leukemia (APL) in a ten-year-old boy. Classical and molecular cytogenetic (FISH) studies of a bone marrow sample obtained at diagnosis revealed the presence of trisom...

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Bibliographic Details
Main Authors: Elenice Ferreira Bastos, Lidiane Alice Silva, Marcelo Coelho Ramos, Glicínia Pimenta, Paulo Ivo Cortez, Stella Beatriz Gonçalves de Lucena, Teresa de Souza Fernandez
Format: Article
Language:English
Published: Hindawi Limited 2012-01-01
Series:Case Reports in Genetics
Online Access:http://dx.doi.org/10.1155/2012/659016