Principles of 3D compartmentalization of the human genome

Summary: Chromatin is organized in the nucleus via CTCF loops and compartmental domains. Here, we compare different cell types to identify distinct paradigms of compartmental domain formation in human tissues. We identify and quantify compartmental forces correlated with histone modifications charac...

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Bibliographic Details
Main Authors: Michael H. Nichols, Victor G. Corces
Format: Article
Language:English
Published: Elsevier 2021-06-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721007063