Impact of DICER1 and DROSHA on the Angiogenic Capacity of Human Endothelial Cells

Impact of DICER1 and DROSHA on the Angiogenic Capacity of Human Endothelial Cells

RNAi-mediated knockdown of DICER1 and DROSHA, enzymes critically involved in miRNA biogenesis, has been postulated to affect the homeostasis and the angiogenic capacity of human endothelial cells. To re-evaluate this issue, we reduced the expression of DICER1 or DROSHA by RNAi-mediated knockdown and...

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Bibliographic Details
Main Authors: Heike Braun, Michael Hauke, Anne Ripperger, Christian Ihling, Matthew Fuszard, Robert Eckenstaler, Ralf A. Benndorf
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
endothelial cells
angiogenesis
microRNA biogenesis
DICER1
DROSHA
RNA interference
Online Access:https://www.mdpi.com/1422-0067/22/18/9855

Internet

https://www.mdpi.com/1422-0067/22/18/9855

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