Improved Production of Recombinant Human β-NGF in Escherichia coli – a Bioreactor Scale Study

Human nerve growth factor β (β-NGF) is considered a major therapeutic agent for treatment of neurodegenerative diseases. We have previously reported the optimized conditions for β-NGF overproduction in Escherichia coli in a shake-flask culture. In this study the optimal %DO (dissolved oxygen) and p...

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Bibliographic Details
Main Authors: POURIA GHOLAMI TILKO, SEYEDEH MAHDIEH SADAT, ZAHRA HAJIHASSAN
Format: Article
Language:English
Published: Exeley Inc. 2018-09-01
Series:Polish Journal of Microbiology
Subjects:
RSM
Online Access:https://www.exeley.com/exeley/journals/polish_journal_of_microbiology/67/3/pdf/10.21307_pjm-2018-045.pdf