Effects of tranilast on the epithelial-to-mesenchymal transition in peritoneal mesothelial cells

Effects of tranilast on the epithelial-to-mesenchymal transition in peritoneal mesothelial cells

Background : We investigated the effects of tranilast on epithelial-to-mesenchymal transition (EMT) in an animal model and on the EMT signaling pathway in human peritoneal mesothelial cells (HPMCs).Methods : We performed in vitro studies (cytotoxicity, cell morphology, and western blot analyses) on...

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Bibliographic Details
Main Authors: Seok Hui Kang, Sang Woon Kim, Keuk Jun Kim, Kyu Hyang Cho, Jong Won Park, Chan-Duck Kim, Jun Young Do
Format: Article
Language:English
Published: The Korean Society of Nephrology 2019-12-01
Series:Kidney Research and Clinical Practice
Subjects:
epithelial-mesenchymal transition
fibrosis
peritoneal dialysis
peritoneum
tranilast
Online Access:https://doi.org/10.23876/j.krcp.19.049

Internet

https://doi.org/10.23876/j.krcp.19.049

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