β-Sitosterol Reduces the Expression of Chemotactic Cytokine Genes in Cystic Fibrosis Bronchial Epithelial Cells

β-Sitosterol Reduces the Expression of Chemotactic Cytokine Genes in Cystic Fibrosis Bronchial Epithelial Cells

Extracts from Nigella arvensis L. seeds, which are widely used as anti-inflammatory remedies in traditional medicine of Northern Africa, were able to inhibit the expression of the pro-inflammatory neutrophil chemokine Interleukin (IL)-8 in Cystic Fibrosis (CF) bronchial epithelial IB3-1 cells expose...

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Bibliographic Details
Main Authors: Ilaria Lampronti, Maria C. Dechecchi, Alessandro Rimessi, Valentino Bezzerri, Elena Nicolis, Alessandra Guerrini, Massimo Tacchini, Anna Tamanini, Silvia Munari, Elisabetta D’Aversa, Alessandra Santangelo, Giuseppe Lippi, Gianni Sacchetti, Paolo Pinton, Roberto Gambari, Maddalena Agostini, Giulio Cabrini
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-05-01
Series:Frontiers in Pharmacology
Subjects:
Nigella arvensis
cystic fibrosis
inflammation
interleukin-8
cytokines
β-sitosterol
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00236/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00236/full

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