Epigenetic silencing of ITGA2 by MiR-373 promotes cell migration in breast cancer.

The loss of ITGA2 plays an important role in cancer metastasis in several solid cancers. However, the molecular mechanism of ITGA2 loss in primary cancers remains unclear. In this study, we found that a lower ITGA2 protein level was observed in breast cancers compared to adjacent non-cancerous breas...

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Bibliographic Details
Main Authors: Wen Ding, Xiao-Lu Fan, Xuan Xu, Jin-Zhou Huang, Song-Hui Xu, Qian Geng, Rong Li, De Chen, Guang-Rong Yan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4530956?pdf=render