Reversal of Alopecia Areata Following Treatment With the JAK1/2 Inhibitor Baricitinib

Reversal of Alopecia Areata Following Treatment With the JAK1/2 Inhibitor Baricitinib

Background: Alopecia areata (AA) is an autoimmune disease resulting in hair loss with devastating psychosocial consequences. Despite its high prevalence, there are no FDA-approved treatments for AA. Prior studies have identified a prominent interferon signature in AA, which signals through JAK molec...

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Bibliographic Details
Main Authors: Ali Jabbari, Zhenpeng Dai, Luzhou Xing, Jane E. Cerise, Yuval Ramot, Yackov Berkun, Gina A. Montealegre Sanchez, Raphaela Goldbach-Mansky, Angela M. Christiano, Raphael Clynes, Abraham Zlotogorski
Format: Article
Language:English
Published: Elsevier 2015-04-01
Series:EBioMedicine
Subjects:
Alopecia areata
Interferon gamma
JAK inhibitor
CANDLE syndrome
Autoimmune disease
Baricitinib
Gene expression profiling
Autoinflammatory
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396415000638

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http://www.sciencedirect.com/science/article/pii/S2352396415000638

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