Serum-Based Quantification of MYCN Gene Amplification in Young Patients with Neuroblastoma: Potential Utility as a Surrogate Biomarker for Neuroblastoma.

Serum-Based Quantification of MYCN Gene Amplification in Young Patients with Neuroblastoma: Potential Utility as a Surrogate Biomarker for Neuroblastoma.

We previously developed a method for determining MYCN gene amplification status using cell-free DNA fragments released from cancer cells into the blood of patients with neuroblastoma (NB). Here, we analyzed the relationship between MYCN amplification (MNA) status and neuroblastoma prognosis. We scre...

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Bibliographic Details
Main Authors: Shigeki Yagyu, Tomoko Iehara, Shiro Tanaka, Takahiro Gotoh, Akiko Misawa-Furihata, Tohru Sugimoto, Wendy B London, Michael D Hogarty, Satoshi Teramukai, Akira Nakagawara, Eiso Hiyama, John M Maris, Hajime Hosoi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4981470?pdf=render

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http://europepmc.org/articles/PMC4981470?pdf=render

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