IL-22 is induced by S100/calgranulin and impairs cholesterol efflux in macrophages by downregulating ABCG1

IL-22 is induced by S100/calgranulin and impairs cholesterol efflux in macrophages by downregulating ABCG1

S100A8/9 and S100A12 are emerging biomarkers for disease activity of autoimmune and cardiovascular diseases. We demonstrated previously that S100A12 accelerates atherosclerosis accompanied by large cholesterol deposits in atherosclerotic lesions of apoE-null mice. The objective of this study was to...

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Bibliographic Details
Main Authors: Bijoy Chellan, Ling Yan, Timothy J. Sontag, Catherine A. Reardon, Marion A. Hofmann Bowman
Format: Article
Language:English
Published: Elsevier 2014-03-01
Series:Journal of Lipid Research
Subjects:
cholesterol transporters
S100A12
receptor for advanced glycation endproducts
peritoneal macrophages
interleukin-22
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520376781

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http://www.sciencedirect.com/science/article/pii/S0022227520376781

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