HIV-1 Nef: a multifaceted modulator of T cell receptor signaling

<p>Abstract</p> <p>Nef, an accessory protein of the Human Immunodeficiency Virus type 1 (HIV-1), is dispensable for viral replication in cell culture, but promotes virus replication and pathogenesis in the infected host. Acting as protein-interaction adaptor, HIV-1 Nef modulates nu...

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Bibliographic Details
Main Authors: Abraham Libin, Fackler Oliver T
Format: Article
Language:English
Published: BMC 2012-12-01
Series:Cell Communication and Signaling
Subjects:
Nef
Online Access:http://www.biosignaling.com/content/10/1/39