Cerebral Blood Perfusion Predicts Response to Sertraline versus Placebo for Major Depressive Disorder in the EMBARC Trial

Background: Major Depressive Disorder (MDD) has been associated with brain-related changes. However, biomarkers have yet to be defined that could “accurately” identify antidepressant-responsive patterns and reduce the trial-and-error process in treatment selection. Cerebral blood perfusion, as measu...

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Bibliographic Details
Main Authors: Crystal M. Cooper, Cherise R. Chin Fatt, Manish Jha, Gregory A. Fonzo, Bruce D. Grannemann, Thomas Carmody, Aasia Ali, Sina Aslan, Jorge R.C. Almeida, Thilo Deckersbach, Maurizio Fava, Benji T. Kurian, Patrick J. McGrath, Melvin McInnis, Ramin V. Parsey, Myrna Weissman, Mary L. Phillips, Hanzhang Lu, Amit Etkin, Madhukar H. Trivedi
Format: Article
Language:English
Published: Elsevier 2019-04-01
Series:EClinicalMedicine
Online Access:http://www.sciencedirect.com/science/article/pii/S2589537019300689