WIN55,212-2, A Dual Modulator of Cannabinoid Receptors and G Protein-Coupled Inward Rectifier Potassium Channels

The coupling of cannabinoid receptors, CB1 and CB2, to G protein-coupled inward rectifier potassium channels, GIRK1 and GIRK2, modulates neuronal excitability in the human brain. The present study established and validated the functional expression in a <i>Xenopus laevis</i> oocyte expre...

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Bibliographic Details
Main Authors: Dongchen An, Steve Peigneur, Jan Tytgat
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/9/5/484