Bone marrow stromal cells from multiple myeloma patients uniquely induce bortezomib resistant NF-κB activity in myeloma cells

<p>Abstract</p> <p>Background</p> <p>Components of the microenvironment such as bone marrow stromal cells (BMSCs) are well known to support multiple myeloma (MM) disease progression and resistance to chemotherapy including the proteasome inhibitor bortezomib. However, f...

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Bibliographic Details
Main Authors: Kim KyungMann, Leith Catherine P, Shi Yufang, Xu Guangwu, O'Connor Shelby L, Callander Natalie S, Markovina Stephanie, Trivedi Parul, Kim Jaehyup, Hematti Peiman, Miyamoto Shigeki
Format: Article
Language:English
Published: BMC 2010-07-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/176