IRF2–INPP4B-mediated autophagy suppresses apoptosis in acute myeloid leukemia cells

IRF2–INPP4B-mediated autophagy suppresses apoptosis in acute myeloid leukemia cells

Abstract Background The present study aimed to investigate the underlying role of interferon-regulatory factor 2 (IRF2)–inositol polyphosphate-4-phosphatase, type-II (INPP4B) axis in the regulation of autophagy in acute myeloid leukemia (AML) cells. Methods Quantitative real time PCR (QRT-PCR) and w...

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Bibliographic Details
Main Authors: Feng Zhang, Jiajia Li, Junfeng Zhu, Lin Liu, Kai Zhu, Shuang Cheng, RuDi Lv, Pingping Zhang
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Biological Research
Subjects:
IRF2
INPP4B
Autophagy
Apoptosis
Acute myeloid leukemia
Online Access:http://link.springer.com/article/10.1186/s40659-019-0218-7

Internet

http://link.springer.com/article/10.1186/s40659-019-0218-7

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