Ocular Gene Therapy with Adeno-associated Virus Vectors: Current Outlook for Patients and Researchers

In this “Perspective”, we discuss ocular gene therapy – the patient's perspective, the various strategies of gene replacement and gene editing, the place of adeno-associated virus vectors, routes of delivery to the eye and the remaining question - “why does immunity continue to limit efficacy?”...

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Bibliographic Details
Main Authors: Geoffrey A. Casey, Kimberly M. Papp, Ian M. MacDonald
Format: Article
Language:English
Published: Knowledge E 2020-08-01
Series:Journal of Ophthalmic & Vision Research
Online Access:https://doi.org/10.18502/jovr.v15i3.7457