Comparative analysis of somatic variant calling on matched FF and FFPE WGS samples

Comparative analysis of somatic variant calling on matched FF and FFPE WGS samples

Abstract Background Research grade Fresh Frozen (FF) DNA material is not yet routinely collected in clinical practice. Many hospitals, however, collect and store Formalin Fixed Paraffin Embedded (FFPE) tumor samples. Consequently, the sample size of whole genome cancer cohort studies could be increa...

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Bibliographic Details
Main Authors: Louise de Schaetzen van Brienen, Maarten Larmuseau, Kim Van der Eecken, Frederic De Ryck, Pauline Robbe, Anna Schuh, Jan Fostier, Piet Ost, Kathleen Marchal
Format: Article
Language:English
Published: BMC 2020-07-01
Series:BMC Medical Genomics
Subjects:
Somatic variants
FFPE
WGS
Precision oncology
Cohort studies
Online Access:http://link.springer.com/article/10.1186/s12920-020-00746-5

Internet

http://link.springer.com/article/10.1186/s12920-020-00746-5

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