Anticancer Effects of Bufalin on Human Hepatocellular Carcinoma HepG2 Cells: Roles of Apoptosis and Autophagy

Anticancer Effects of Bufalin on Human Hepatocellular Carcinoma HepG2 Cells: Roles of Apoptosis and Autophagy

The traditional Chinese medicine bufalin, extracted from toad’s skin, has been demonstrated to exert anticancer activities in various kinds of human cancers. The mechanisms of action lie in its capacity to induce apoptosis, or termed type I programmed cell death (PCD). However, type II...

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Bibliographic Details
Main Authors: Jian Zhang, Yan-Hua Xie, Qian Yang, Song Zhang, Jin Zhang, Shan Miao, Xin Li, Lin-Lin Bi, Qing Miao, Si-Wang Wang
Format: Article
Language:English
Published: MDPI AG 2013-01-01
Series:International Journal of Molecular Sciences
Subjects:
hepatocellular carcinoma
bufalin
apoptosis
autophagy
AMPK
mTOR
Online Access:http://www.mdpi.com/1422-0067/14/1/1370

Internet

http://www.mdpi.com/1422-0067/14/1/1370

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