Pregnane X receptor in drug-induced liver injury: Friend or foe?
The pregnane X receptor (PXR) is a ligand activated nuclear receptor that is highly expressed in the liver and regulates many cellular functions including drug metabolism, endobiotic metabolism, oxidative stress response, apoptosis, inflammation, cell proliferation and regeneration. PXR activation p...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
KeAi Communications Co., Ltd.
2018-12-01
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| Series: | Liver Research |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S254256841830045X |