Human synapses show a wide temporal window for spike-timing-dependent plasticity

Human synapses show a wide temporal window for spike-timing-dependent plasticity

Throughout our lifetime, activity-dependent changes in neuronal connection strength enable the brain to refine neural circuits and learn based on experience. Synapses can bi-directionally alter strength and the magnitude and sign depend on the millisecond timing of presynaptic and postsynaptic actio...

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Bibliographic Details
Main Authors: Guilherme T Silva, Matthijs B Verhoog, Natalia B Goriounova, Alex Loebel, Johannes Hjorth, Johannes C Baayen, Christiaan P J De Kock, Huibert D Mansvelder
Format: Article
Language:English
Published: Frontiers Media S.A. 2010-07-01
Series:Frontiers in Synaptic Neuroscience
Subjects:
Hippocampus
Neocortex
human
synaptic plasticity
synapse
Hebbian plasticity
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnsyn.2010.00012/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnsyn.2010.00012/full

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