GIN'n'CIN hypothesis of brain aging: deciphering the role of somatic genetic instabilities and neural aneuploidy during ontogeny
<p>Abstract</p> <p>Genomic instability (GIN) and chromosome instability (CIN) are two closely related ways to produce a variety of pathogenic conditions, i.e. cancer, neurodegeneration, chromosomal and genomic diseases. The GIN and CIN manifestation that possesses the most apprecia...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2009-11-01
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Series: | Molecular Cytogenetics |
Online Access: | http://www.molecularcytogenetics.org/content/2/1/23 |