Empirical Bayes accomodation of batch-effects in microarray data using identical replicate reference samples: application to RNA expression profiling of blood from Duchenne muscular dystrophy patients

Empirical Bayes accomodation of batch-effects in microarray data using identical replicate reference samples: application to RNA expression profiling of blood from Duchenne muscular dystrophy patients

<p>Abstract</p> <p>Background</p> <p>Non-biological experimental error routinely occurs in microarray data collected in different batches. It is often impossible to compare groups of samples from independent experiments because batch effects confound true gene expressio...

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Bibliographic Details
Main Authors: McCulloch Charles E, Pollard Katherine S, Wong Brenda, Gilbert Donald L, Liao Isaac H, Walker Wynn L, Lit Lisa, Sharp Frank R
Format: Article
Language:English
Published: BMC 2008-10-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/9/494

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http://www.biomedcentral.com/1471-2164/9/494

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