Human breast cancer cell-mediated bone collagen degradation requires plasminogen activation and matrix metalloproteinase activity
<p>Abstract</p> <p>Background</p> <p>Breast cancer cells frequently metastasize to the skeleton and induce extensive bone destruction. Cancer cells produce proteinases, including matrix metalloproteinases (MMPs) and the plasminogen activator system (PAS) which promote i...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2005-02-01
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| Series: | Cancer Cell International |
| Online Access: | http://www.cancerci.com/content/5/1/1 |