The feelgood mutation in zebrafish dysregulates COPII-dependent secretion of select extracellular matrix proteins in skeletal morphogenesis

The feelgood mutation in zebrafish dysregulates COPII-dependent secretion of select extracellular matrix proteins in skeletal morphogenesis

SUMMARY Craniofacial and skeletal dysmorphologies account for the majority of birth defects. A number of the disease phenotypes have been attributed to abnormal synthesis, maintenance and composition of extracellular matrix (ECM), yet the molecular and cellular mechanisms causing these ECM defects r...

Full description

Bibliographic Details
Main Authors: David B. Melville, Mercedes Montero-Balaguer, Daniel S. Levic, Kevin Bradley, Jeffrey R. Smith, Antonis K. Hatzopoulos, Ela W. Knapik
Format: Article
Language:English
Published: The Company of Biologists 2011-11-01
Series:Disease Models & Mechanisms
Online Access:http://dmm.biologists.org/content/4/6/763

Internet

http://dmm.biologists.org/content/4/6/763

Similar Items