Differential Cellular Responses to Hedgehog Signalling in Vertebrates—What is the Role of Competence?

A surprisingly small number of signalling pathways generate a plethora of cellular responses ranging from the acquisition of multiple cell fates to proliferation, differentiation, morphogenesis and cell death. These diverse responses may be due to the dose-dependent activities of signalling factors,...

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Bibliographic Details
Main Authors: Clemens Kiecker, Anthony Graham, Malcolm Logan
Format: Article
Language:English
Published: MDPI AG 2016-12-01
Series:Journal of Developmental Biology
Subjects:
IRX
Online Access:http://www.mdpi.com/2221-3759/4/4/36