A Bacterial Epigenetic Switch in Non-typeable Haemophilus influenzae Modifies Host Immune Response During Otitis Media

A Bacterial Epigenetic Switch in Non-typeable Haemophilus influenzae Modifies Host Immune Response During Otitis Media

Non-typeable Haemophilus influenzae (NTHi) causes multiple diseases of the human airway and is a predominant bacterial pathogen of acute otitis media and otitis media in which treatment fails. NTHi utilizes a system of phase variable epigenetic regulation, termed the phasevarion, to facilitate adapt...

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Bibliographic Details
Main Authors: Frank H. Robledo-Avila, Juan de Dios Ruiz-Rosado, Santiago Partida-Sanchez, Kenneth L. Brockman
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
NTHI
otitis media (OM)
phasevarion
chinchilla
neutrophil
biofilm
Online Access:https://www.frontiersin.org/articles/10.3389/fcimb.2020.512743/full

Internet

https://www.frontiersin.org/articles/10.3389/fcimb.2020.512743/full

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