Comparing Interfacial Trp, Interfacial His and pH Dependence for the Anchoring of Tilted Transmembrane Helical Peptides

Charged and aromatic amino acid residues, being enriched toward the terminals of membrane-spanning helices in membrane proteins, help to stabilize particular transmembrane orientations. Among them, histidine is aromatic and can be positively charge at low pH. To enable investigations of the underlyi...

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Bibliographic Details
Main Authors: Fahmida Afrose, Roger E. Koeppe II
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/10/2/273