The Reprimo-Like Gene ISs an Epigenetic-Mediated Tumor Suppressor and a Candidate Biomarker for the Non-Invasive Detection of Gastric Cancer

The Reprimo-Like Gene ISs an Epigenetic-Mediated Tumor Suppressor and a Candidate Biomarker for the Non-Invasive Detection of Gastric Cancer

Reprimo-like (<i>RPRML</i>) is an uncharacterized member of the Reprimo gene family. Here, we evaluated the role of <i>RPRML</i> and whether its regulation by DNA methylation is a potential non-invasive biomarker of gastric cancer. RPRML expression was evaluated by immunohist...

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Bibliographic Details
Main Authors: María Alejandra Alarcón, Wilda Olivares, Miguel Córdova-Delgado, Matías Muñoz-Medel, Tomas de Mayo, Gonzalo Carrasco-Aviño, Ignacio Wichmann, Natalia Landeros, Julio Amigo, Enrique Norero, Franz Villarroel-Espíndola, Arnoldo Riquelme, Marcelo Garrido, Gareth I. Owen, Alejandro H. Corvalán
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
biomarkers
gastric cancer
plasma
non-invasive
methylation
intronless
Online Access:https://www.mdpi.com/1422-0067/21/24/9472

Internet

https://www.mdpi.com/1422-0067/21/24/9472

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