Effects of PPARs agonists on cardiac metabolism in littermate and cardiomyocyte-specific PPAR-γ-knockout (CM-PGKO) mice.

Understanding the molecular regulatory mechanisms controlling for myocardial lipid metabolism is of critical importance for the development of new therapeutic strategies for heart diseases. The role of PPARγ and thiazolidinediones in regulation of myocardial lipid metabolism is controversial. The ai...

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Bibliographic Details
Main Authors: Michelangela Barbieri, Clara Di Filippo, Antonietta Esposito, Raffaele Marfella, Maria Rosaria Rizzo, Michele D'Amico, Franca Ferraraccio, Cristina Di Ronza, Sheng Zhong Duan, Richard M Mortensen, Francesco Rossi, Giuseppe Paolisso
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3338561?pdf=render