The Non-synonymous rs763780 Single-Nucleotide Polymorphism in IL17F Gene Is Associated With Susceptibility to Tuberculosis and Advanced Disease Severity in Argentina

The Non-synonymous rs763780 Single-Nucleotide Polymorphism in IL17F Gene Is Associated With Susceptibility to Tuberculosis and Advanced Disease Severity in Argentina

Th17 lymphocytes, that produce IL17A, IL17F, and IL22, play a crucial role during the immune response against Mycobacterium tuberculosis (Mtb) infection. Whereas, the contribution of IL17A in immunity to tuberculosis is usually accepted, the role of IL17F has been scarcely studied so far. The aim of...

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Bibliographic Details
Main Authors: Agustín Rolandelli, Joaquín Miguel Pellegrini, Rodrigo Emanuel Hernández Del Pino, Nancy Liliana Tateosian, Nicolás Oscar Amiano, María Paula Morelli, Florencia Andrea Castello, Nicolás Casco, Alberto Levi, Domingo Juan Palmero, Verónica Edith García
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-09-01
Series:Frontiers in Immunology
Subjects:
tuberculosis
Th17
IL17F
single-nucleotide polymorphism
rs763780
immunogenetics
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02248/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02248/full

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