Computational Methods for Detection of Differentially Methylated Regions Using Kernel Distance and Scan Statistics

Motivation: Researchers in genomics are increasingly interested in epigenetic factors such as DNA methylation because they play an important role in regulating gene expression without changes in the sequence of DNA. Abnormal DNA methylation is associated with many human diseases. Results: We propose...

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Bibliographic Details
Main Authors: Faith Dunbar, Hongyan Xu, Duchwan Ryu, Santu Ghosh, Huidong Shi, Varghese George
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Genes
Subjects:
Online Access:https://www.mdpi.com/2073-4425/10/4/298