Effect and Mechanism of TL1A Expression on Epithelial-Mesenchymal Transition during Chronic Colitis-Related Intestinal Fibrosis

Background and Aims. Recent evidences reveal that epithelial to mesenchymal transition (EMT) exacerbates the process of intestinal fibrosis. Tumor necrosis factor-like ligand 1A (TL1A) is a member of the tumor necrosis family (TNF), which can take part in the development of colonic inflammation and...

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Bibliographic Details
Main Authors: Jia Wenxiu, Yang Mingyue, Han Fei, Luo Yuxin, Wu Mengyao, Li Chenyang, Song Jia, Zhang Hong, David Q. Shih, Stephan R. Targan, Zhang Xiaolan
Format: Article
Language:English
Published: Hindawi Limited 2021-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2021/5927064