Centrosomal pre-integration latency of HIV-1 in quiescent cells

<p>Abstract</p> <p>Human immunodeficiency virus type 1 (HIV-1) efficiently replicates in dividing and non-dividing cells. However, HIV-1 infection is blocked at an early post-entry step in quiescent CD4+ T cells <it>in vitro</it>. The molecular basis of this restriction...

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Main Authors: Emiliani Stéphane, Roingeard Philippe, Tobaly-Tapiero Joëlle, Giron Marie-Lou, Clave Emmanuel, Lehmann-Che Jacqueline, Zamborlini Alessia, Toubert Antoine, de Thé Hugues, Saïb Ali
Format: Article
Language:English
Published: BMC 2007-09-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/4/1/63