Design and experimental validation of the action of small molecule-based inhibitors of the FADD protein
CD95 is one of the best studied members of the death receptor family. Activation of CD95 leads to the induction of the cell death programme, apoptosis, via formation of the death-inducing signaling complex (DISC). FA DD is a key adaptor protein for the formation of the C D95 DISC and activation of c...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Institute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences
2016-01-01
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Series: | Vavilovskij Žurnal Genetiki i Selekcii |
Subjects: | |
Online Access: | https://vavilov.elpub.ru/jour/article/view/490 |