Exosome release and neuropathology induced by α-synuclein: new insights into protective mechanisms of Drp1 inhibition
Abstract Targeting alpha-synuclein (α-syn) as a therapeutic strategy for Parkinson’s disease (PD) has been intensively pursued largely due to its well-recognized pathogenic role. Since its discovery as the first familial link to PD over two decades ago, this protein has been associated with multiple...
Main Authors: | Rebecca Z. Fan, Min Guo, Shouqing Luo, Mei Cui, Kim Tieu |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-11-01
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Series: | Acta Neuropathologica Communications |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s40478-019-0821-4 |
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