New Oxidovanadium(IV) Coordination Complex Containing 2-Methylnitrilotriacetate Ligands Induces Cell Cycle Arrest and Autophagy in Human Pancreatic Ductal Adenocarcinoma Cell Lines

New Oxidovanadium(IV) Coordination Complex Containing 2-Methylnitrilotriacetate Ligands Induces Cell Cycle Arrest and Autophagy in Human Pancreatic Ductal Adenocarcinoma Cell Lines

Pancreatic cancer is characterized by one of the lowest five-year survival rates. In search for new treatments, some studies explored several metal complexes as potential anticancer drugs. Therefore, we investigated three newly synthesized oxidovanadium(IV) complexes with 2-methylnitrilotriacetate (...

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Bibliographic Details
Main Authors: Szymon Kowalski, Dariusz Wyrzykowski, Stanislaw Hac, Michal Rychlowski, Marek Witold Radomski, Iwona Inkielewicz-Stepniak
Format: Article
Language:English
Published: MDPI AG 2019-01-01
Series:International Journal of Molecular Sciences
Subjects:
Vanadium complex
pancreatic cancer
autophagy
mitotic catastrophe
cell cycle arrest
Online Access:http://www.mdpi.com/1422-0067/20/2/261

Internet

http://www.mdpi.com/1422-0067/20/2/261

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