Construction of Interferon-Gamma-Related Gene Signature to Characterize the Immune-Inflamed Phenotype of Glioblastoma and Predict Prognosis, Efficacy of Immunotherapy and Radiotherapy

Construction of Interferon-Gamma-Related Gene Signature to Characterize the Immune-Inflamed Phenotype of Glioblastoma and Predict Prognosis, Efficacy of Immunotherapy and Radiotherapy

Interferon-gamma (IFNG) has profound impacts on tumor-immune interaction and is of great clinical significance for multiple cancers. Exploring the role of IFNG in glioblastoma (GBM) may optimize the current treatment paradigm of this disease. Here, multi-dimensional data of 429 GBM samples were coll...

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Bibliographic Details
Main Authors: Hang Ji, Yixu Ba, Shuai Ma, Kuiyuan Hou, Shan Mi, Xin Gao, Jiaqi Jin, Qin Gong, Ting Liu, Fang Wang, Zhihui Liu, Shupeng Li, Jianyang Du, Shaoshan Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
glioblastoma
interferon-gamma
tumor immune microenvironment
IFNG-related gene signature
anti-tumor immune response
immune checkpoint blockade therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.729359/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2021.729359/full

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