Improved Homology Model of the Human all-trans Retinoic Acid Metabolizing Enzyme CYP26A1

A new CYP26A1 homology model was built based on the crystal structure of cyanobacterial CYP120A1. The model quality was examined for stereochemical accuracy, folding reliability, and absolute quality using a variety of different bioinformatics tools. Furthermore, the docking capabilities of the mode...

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Bibliographic Details
Main Authors: Mohamed K. A. Awadalla, Thamir M. Alshammari, Leif A. Eriksson, Patricia Saenz-Méndez
Format: Article
Language:English
Published: MDPI AG 2016-03-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/21/3/351