Engrailed 2 (EN2) acts as a glioma suppressor by inhibiting tumor proliferation/invasion and enhancing sensitivity to temozolomide

Abstract Background Glioma is one of the most malignant brain tumors and accounts for the majority of brain cancer related death. Despite progress on mechanistic studies, current understandings of the initiation and progression of glioma are still incomplete. Previous studies demonstrate that Engrai...

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Bibliographic Details
Main Authors: Tengfei Li, Wanchun Yang, Mao Li, Shuxin Zhang, Xingwang Zhou, Mingrong Zuo, Qiuyun Yuan, Mina Chen, Yanhui Liu
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Cancer Cell International
Subjects:
EN2
Online Access:http://link.springer.com/article/10.1186/s12935-020-1145-y