Genetic and behavioral adaptation of Candida parapsilosis to the microbiome of hospitalized infants revealed by in situ genomics, transcriptomics, and proteomics

Genetic and behavioral adaptation of Candida parapsilosis to the microbiome of hospitalized infants revealed by in situ genomics, transcriptomics, and proteomics

Abstract Background Candida parapsilosis is a common cause of invasive candidiasis, especially in newborn infants, and infections have been increasing over the past two decades. C. parapsilosis has been primarily studied in pure culture, leaving gaps in understanding of its function in a microbiome...

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Bibliographic Details
Main Authors: Patrick T. West, Samantha L. Peters, Matthew R. Olm, Feiqiao B. Yu, Haley Gause, Yue Clare Lou, Brian A. Firek, Robyn Baker, Alexander D. Johnson, Michael J. Morowitz, Robert L. Hettich, Jillian F. Banfield
Format: Article
Language:English
Published: BMC 2021-06-01
Series:Microbiome
Subjects:
Microbial eukaryotes
Metagenomics
Genome-resolved metagenomics
Strain-tracking
Hospital microbiome
Neonatal intensive care unit
Online Access:https://doi.org/10.1186/s40168-021-01085-y

Internet

https://doi.org/10.1186/s40168-021-01085-y

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